I had a devastating bubble algae in my 70 gallon tank. Literally bubble algae over every single rock and squeezing out and killing zoas. I tried everything. Emerald crabs were eaten by my eel. A rabbitfish showed no interest in them. I used Vibrant at high dose level for several months with zero impact (also zero impact on other algae - my experience is it's useless but there are plenty of success stories on Reef2Reef; fake news?). I took every single rock out of the tank and manually removed the bubble algae. It was back taking over the tank in a matter of months.
Finally I saw thread by Chris A on his success with Reef HD so decided to try it. I ran it four weeks at 4x (no skimmer, chaeto removed from refugium, no water changes) and it wiped out all the algae in tank but not the bubble algae though it looked less healthy. I gave the tank two weeks with water change and skimming, then ran REEF HD at 8x for 4 weeks. Within two weeks the bubble algae was completely gone. Two weeks after treatment still don't see any. Highly recommend it though it's not cheap. I have refugium sump and 40 breeder in system so cost me about 150 dollars to run the treatments. Tank has large quantity of zoas, euphyllis and hardy sps and none of it was affected at all.
Finally I saw thread by Chris A on his success with Reef HD so decided to try it. I ran it four weeks at 4x (no skimmer, chaeto removed from refugium, no water changes) and it wiped out all the algae in tank but not the bubble algae though it looked less healthy. I gave the tank two weeks with water change and skimming, then ran REEF HD at 8x for 4 weeks. Within two weeks the bubble algae was completely gone. Two weeks after treatment still don't see any. Highly recommend it though it's not cheap. I have refugium sump and 40 breeder in system so cost me about 150 dollars to run the treatments. Tank has large quantity of zoas, euphyllis and hardy sps and none of it was affected at all.