Last research I read about was that red bugs (Tegastes acroporanus) under observation did not live after 5 days, 120 hours without a host. The hosts are corals under the genus Acropora, but not all species of Acropora corals. There is a broad spectrum of medicinal dosages that can be used as Acropora seem to be fairly resilient to it (interceptor). There have been a few cases in which there was coral die off. Duration of the treatment is very important regardless of the amount of medication dosed.