I would think if placed correctly they could. Ever seen a swamp cooler? They use them down south a lot. They trickle water down a mesh filter while sucking air in through them and out another end. You'd be amazed at how evaporation can cool something. Here's a link about it. http://www.wonderquest.com/swamp-coolers.htmthis is me said:that still require your room to be AC right? No way a couple of fan can lower the temp by 8 degree.